Acanthosis nigricans
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Tha Acanthosis nigricans na dhearbhadh geur air suidheachadh bunaiteach. Bidh e tric a’ nochdadh ann am pìosan craiceann mar amhach, armpits, agus groin, a’ coimhead coltach ri badan dorcha meurach le oirean neo-shoilleir. Mar as trice bidh an suidheachadh seo ceangailte ri tinneas an t-siùcair agus strì an aghaidh insulin, ach ann an cùisean ainneamh, dh’ fhaodadh e aillse taobh a-staigh na bodhaig a chomharrachadh. Dh'fhaodadh e cuideachd nochdadh mar thoradh air cùisean hormona no bho bhith a 'toirt cungaidhean-leigheis sònraichte leithid steroids agus pills smachd breith.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Tha Acanthosis nigricans (AN) na staid craiceann cumanta ceangailte ri diofar chùisean slàinte leithid strì an aghaidh insulin, tinneas an t-siùcair, reamhrachd, cansearan sònraichte, duilgheadasan hormonail, agus ath-bheachdan air cungaidhean-leigheis. Tha làimhseachadh AN ag amas air dèiligeadh ris na duilgheadasan slàinte bunaiteach. An toiseach, bidh dotairean a 'sgrùdadh airson comharran de shionndrom frith-insulin, a tha a' gabhail a-steach reamhrachd, colaistéarol àrd, bruthadh-fala àrd, agus tinneas an t-siùcair seòrsa 2. Bidh dotairean gu tric ag òrdachadh topical retinoids mar a’ chiad roghainn làimhseachaidh, a chuidicheas le tiugh craiceann. Ach, dh'fhaodadh nach bi iad a 'dèiligeadh gu tur ri dorchadas craiceann. Feumaidh roghainnean làimhseachaidh eile (salicylic acid, podophyllin, urea, calcipotriol) tagradh tric cuideachd.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
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Mar as trice bidh e a’ tachairt ann an daoine fo aois 40, dh’ fhaodadh a bhith air an sealbhachadh gu ginteil agus tha e co-cheangailte ri reamhrachd no endocrinopathies, leithid hypothyroidism, acromegaly, galar ovary polycystic, tinneas an t-siùcair a tha an aghaidh insulin no galar Cushing.
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